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Genetically Engineered, HIV-Resistant Cells: The Latest Breakthrough in HIV Gene Therapy


A new gene therapy could make a person's CD4+ cells resistant to HIV — a method that, if successful, would eliminate the need for antiretroviral drugs for those living with HIV, according to a new study conducted by researchers at the Stanford University School of Medicine.

HIV replicates by infecting a person's CD4+ cells, which the virus enters through the CCR5 receptor (or, in rare cases, the CXCR4 receptor) found on the CD4+ cell surface. Inactivating these receptors would block HIV from entering the cells.

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